City looks to restart search to develop long-vacant Roxbury site

The team behind the 1.7-million-square-foot proposal dubbed Tremont Crossing lost $30 million in predevelopment financing about two weeks ago, Director Brian Golden of the Boston Planning & Development Agency says, and the group could not point to another source of funds.

“I think there’s going to be a bloodbath if the rates reset to the higher level,” said Dave Willis, cofounder of Bully Boy Distillers in Roxbury. “For the smaller guys it will be a horrifying wake-up call.”

Spiked punch: Tax hikes and tariffs will make holiday parties more expensive

The new charges have local business owners on edge as they prepare for one of their busiest times of the year.

A laptop displayed a message after being infected by a ransomware attack.

Mass. lawmakers call for US crackdown on ransomware attacks

Senators Elizabeth Warren and Edward Markey, along with eight of the state’s representatives, asked Homeland Security for more help with a problem that has affected communities across the state.

A rendering of a possible look for the redevelopment.

Suits over waterfront zoning can go to trial, judge says

The new zoning would enable developer Don Chiofaro to build a massive waterfront tower along the edge of Boston Harbor.

Latest Business headlines

Johnson & Johnson recalls asbestos-tainted baby powder

Johnson & Johnson is recalling a shipment of baby powder after the Food and Drug Administration discovered evidence of asbestos in one of the bottles, the company said Friday, a move that undercuts its defense in a growing number of claims that its talc-based products were contaminated with the potent carcinogen.

Boeing pilot complained of ‘egregious’ issue with 737 Max in 2016

A Boeing pilot working on the 737 Max said in messages from 2016 that a new automated system was making the plane difficult to control in flight simulators, more than two years before it was grounded after two deadly crashes.

FAA confronts Boeing over undisclosed 737 Max internal safety communication

A pilot at Boeing had expressed concern three years ago over the flight control system that has been implicated in two fatal crashes, but the company waited months to disclose them.

Shirley Leung

Honey Dew, Dunkin’ toss out Styrofoam cups, but is it enough to save the planet?

This month Honey Dew will make the switch to double-walled paper cups at all of its locations. Dunkin’ is on track to eliminate the foam cup in New England by year’s end.

J&J agrees to $117m settlement over pelvic mesh devices

The pact would resolve allegations Johnson & Johnson deceptively marketed its pelvic mesh products, which support women’s sagging pelvic organs.

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Sean P. Murphy is the Globe’s consumer columnist, and he’s here to take your queries.

Globe Magazine

Top Places to Work

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/11/14/BostonGlobe.com/Magazine/Images/intro2018tptw.jpg The 2018 Top Places to Work in Massachusetts

These 128 businesses have the happiest employees in the state. Here are sortable lists of the winners, and how we compiled them.

STAT

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2019/05/02/BostonGlobe.com/National/Images/gel.jpg Developing new antibiotics requires new incentives, experts say

The private sector is unwilling to take on the financial risk, experts say, despite desperate need.

More Business headlines

A member of the union carried a copy of the contract settlement agreement outside of the UAW GM Council Meeting Thursday in Detroit.

GM Deal Saves One Plant, Union Says, but 3 Others Stay Shut

DETROIT — General Motors has agreed to continue production at a Detroit plant it had planned to shut down, but will not resume operations at three others recently idled, the United Automobile Workers union said Thursday in announcing the terms of a tentative contract agreement.

Necco stopped production at its Revere plant in 2018.

CHESTO MEANS BUSINESS

Revere gets its Amazon after all

After failing in the HQ2 sweepstakes, Revere will host a giant Amazon facility at the former Necco candy factory.

Weekend agenda

A brunch benefiting cancer research, a career fair for students interested in conservation, and other events and things to know.

Juul products were displayed at a smoke shop in New York.

As concern grows about teen vaping, Juul suspends online sales of flavored e-cigarettes

Juul Labs is facing multiple federal and state investigations into its marketing practices as outrage mounts over the soaring rate of teenage vaping.

Boston Global Investors and CIM Group received approval to build a 310-foot condo tower atop the Motor Mart Garage in Back Bay.

The Motor Mart Garage will get a glassy new tower on top

The BPDA board blessed plans for a 310-foot building atop the garage on Stuart Street, next to the Park Plaza Hotel.

John Hancock proposed building an office tower (rendering above) on Stuart Street.

John Hancock pulls out of building new Back Bay tower

The insurance giant will sell off the land and development rights for the Stuart Street property.

After some wobbling, stocks close higher on solid earnings

A breakthrough in negotiations over Britain’s exit from the European Union also helped put traders in a buying mood.

Lisa Goldblatt Grace of My Life My Choice, an organization that fights sex trafficking and mentors young people to nudge them away from sexual exploitation.

WORK SPACE

A ‘Boss Lady’ and a new approach to fighting sex trafficking

The organization My Life My Choice sees the world from the perspective of survivors as it fights the commercial sexual exploitation of children. And its employees believe that the best way to promote understanding is by amplifying the real voices of real people.

Facebook founder Mark Zuckerberg spoke Thursday at Georgetown University.

Mark Zuckerberg defends allowing politicians to lie in ads

Zuckerberg defended the policy that allows politicians to peddle ads containing misrepresentations and lies on Facebook.

Years after Massachusetts health insurers launched websites to help consumers make sense of medical costs, the tools are seldom used and are failing to contain health spending as hoped, according to a new report from Attorney General Maura Healey’s office.

AG says price transparency isn’t helping consumers save on health care costs

The analysis injects fresh skepticism into the popular theory that giving consumers more information about the cost of medical services will compel them to choose lower-cost health care providers.

FILE -- McKesson Corporation's headquarters in San Francisco, April 5, 2019. The nation’s three largest drug distributors, including McKesson, as well as two manufacturers, are in negotiations to settle thousands of cases before a trial set to begin on Monday, Oct. 21. (Anastasiia Sapon/The New York Times)

Opioid settlement talks broaden ahead of 1st federal trial

Efforts to settle thousands of lawsuits related to the nation’s opioid epidemic were intensifying Wednesday, just days ahead of the scheduled start of arguments in the first federal trial over the crisis.

Business agenda

Mortgage rates, social mixers, and other events and things to know.

J&J Makes $4 Billion Opioid Offer as Distributors Seek Deal

Johnson & Johnson has offered to pay $4 billion to settle all claims accusing the company of helping fuel the U.S. opioid epidemic, as part of a potentially larger deal involving drugmakers and distributors that could top $20 billion.

The MBTA last week approved transferring its commuter ferry contract to BHC’s new owner.

Chesto Means Business

Boston Harbor Cruises is sold to a Chicago ferry operator

The sale to Hornblower Holdings follows nearly a century of family ownership.

European Commissioner for Competition Margrethe Vestager speaks during a media conference regarding an anti-trust decision at EU headquarters in Brussels, Wednesday, Oct. 16, 2019. (AP Photo/Virginia Mayo)

Europe’s antitrust regulator takes a rare step toward big tech

European authorities took an even more aggressive approach than usual to regulating the technology industry Wednesday when they applied a rarely used rule, ordering a company to halt a potentially anticompetitive practice while an investigation is underway.

Tech companies lead modest slide by US stock indexes

A day of mostly listless trading on Wall Street ended Wednesday with modest losses as the stock market gave back some of its gains from the day before.

Boston biotech Alexion Pharmaceuticals said Wednesday that it will acquire Achillion Pharmaceuticals to expand its pipeline of experimental drugs targeting rare diseases of the immune system.

Boston biotech Alexion to acquire Achillion Pharmaceuticals for $930 million

For Alexion, the decision to buy Achillion is part of a broader and ongoing plan to diversify its pipeline of experimental drugs targeting rare diseases of the immune system.

When the T breaks down, we can watch the agony unfold on social media. Harder to detect is the fallout from a housing crisis. We don’t see it when people can’t afford the rent, can’t buy the home they want, or can’t stay in the state because the cost of living is too high.

SHIRLEY LEUNG

We need more — and faster — fixes for the housing crisis

It’s difficult to detect the fallout from our housing crisis. We don’t see it when people can’t afford the rent, can’t buy the home they want, or can’t stay in the state because the cost of living is too high.

Ken Fisher, head of Fisher Investments, has apologized for remarks he made at a conference.

City pulls $248m in pension money from firm after CEO’s off-color comments on women

The City of Boston on Wednesday terminated its relationship with billionaire money manager Ken Fisher following lewd comments he made last week.

X-ray image of a human chest.

Blueprint, French drug maker Ipsen to work on treatment for ultra-rare genetic disorder

Under the agreement, Blueprint and Ipsen will work together to develop and market a drug to treat fibrodysplasia ossificans progressiva, or FOP, an incurable disease that turns muscles, tendons, and ligaments into bone.

Union members picketed outside a GM facility in Pa. last month.

GM, union reach tentative deal that could end monthlong strike

The deal could end the monthlong strike and get some 49,000 workers back on the job.

FILE - In this May 8, 2019, file photo a Boeing 737 MAX 8 jetliner being built for Turkish Airlines takes off on a test flight in Renton, Wash. Passengers who refuse to fly on a Boeing Max won’t be entitled to compensation if they cancel. However, travel experts think airlines will be very flexible in rebooking passengers of giving them refunds if they’re afraid to fly on a plane that has crashed twice. (AP Photo/Ted S. Warren, File)

Worried about flying on a 737 Max? Your options may be few

At some point early next year, air travelers will need to decide if they’re willing to take a flight on a Boeing 737 Max.

Dr. Wiliam G. Kaelin, Jr.

STAT live: Chat with 2019 Nobel recipient William Kaelin Jr.

Kaelin will answer questions about his lab’s research on how cells sense and adapt to oxygen levels — and how those discoveries could help develop treatments for diseases including cancer and anemia.

A rendering of the proposed 51-story tower above South Station.

Work on long-delayed South Station tower may finally start

More than a decade after it was first proposed, construction of a 51-story tower atop South Station could soon start, now that its builders have lined up deep-pocketed new investors.

Business agenda

A workshop for creative businesses, a tour through some of Boston’s most famous offices, and other events and things to know.

Bob Luz says more should be done to promote this state’s status as a “great culinary destination.”

Jon Chesto|Chesto Means Business

Legislature’s $2M gift prompts some soul-searching in restaurant industry

House Speaker Bob DeLeo gave the restaurant industry a sweet gift this summer. But that present is going to take some time to unwrap.

Columbia Gas workers on South Broadway in Lawrence in September after one of the pipes replaced due to last year's explosions sprung a leak, forcing another evacuation of the neighborhood.

NiSource brings former National Grid exec in an effort to regain customers’ trust

NiSource Inc. on Tuesday announced it had hired Nick Stavropoulos to a newly created, senior role: chief safety officer for Columbia Gas of Massachusetts.

Kate Walsh

BOLD TYPES

Defying expectations, hospital’s fund-raising brings in $450m

Bold Types: Boston Medical Center just celebrated the end of six years of fund-raising, ringing up a total that would be the envy of most hospitals: $450 million.

FILE - In this July 16, 2019, file photo General Motors Chairman and Chief Executive Officer Mary Barra speaks during the opening of their contract talks with the United Auto Workers in Detroit. On Tuesday, Oct. 15, Barra joined negotiators at the bargaining table, an indication that a deal may be near to end a monthlong strike by members of the United Auto Workers union that has paralyzed its factories. (AP Photo/Paul Sancya, File)

End in sight? GM CEO Barra joins talks with striking union

General Motors chief executive Mary Barra joined negotiators at the bargaining table, an indication that a deal may be near to end a monthlong strike by the United Auto Workers union that has paralyzed the company’s factories.

Nevada gaming regulators move to ban casino mogul Steve Wynn

The Nevada Gaming Control Board accused the former chairman and chief executive of Wynn Resorts of violating state regulations and said he was ‘‘unsuitable to be associated with a gaming enterprise or the gaming industry as a whole.’’

The Wanyoo Gaming Cafe in Malden has attracted a following as e-sports grow in popularity.

In Malden, fun and games are big business

From video competition to escape rooms, the city’s downtown has become an “e-sports” destination.

The Roomba i7+ maps your home, schedules sweeps through each room, empties the dust bin itself, and even knows where to resume cleaning after it has returned to its base for a recharge.

Bedford-based iRobot sues upstart SharkNinja of Needham

After one of its products was recognized by Time magazine as a 2018 invention of the year, iRobot Corp. says it’s no accident that rival SharkNinja Operating LLC came out with a similar device a year later.

Solid company earnings power broad rally for US stocks

Investors welcomed surprisingly good quarterly results from some of the nation’s biggest companies.

The scene inside the MGM Springfield casino. It took in just under $20 million in September.

September was another lackluster month for the state’s casinos

Overall revenue at the Encore Boston Harbor casino came in at $49 million in its third full month of operation, down from a haul of $52.5 million in August.

A rendering of the inside of the Roche Bros. Brothers Marketplace store in Kendall Square, which will open Nov. 12.

A new Roche Bros. grocery store will open in Kendall Square next month

A long-awaited supermarket is finally opening in Cambridge’s One Broadway.

WeWork, landlord scrap deal for 36-story Seattle tower lease

The company has backed out of an ambitious project to outfit a 36-story tower in Seattle with co-working space and its co-living offshoot, as it looks to shore up its finances.

WORK SPACE

Andrew Lelling fills his office with meaning

The US Attorney for Boston says it’s important that his waterfront office features “things I care about.”

CAMBRIDGE, MA - OCTOBER 14, 2019: Esther Duflo and Abhijit Banerjee speak with the media and guests after being named co-winners of the 2019 Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel during a press conference at MIT in Cambridge, MA on October 14, 2019. They shared the prize with Harvard University economist Michael Kremer. (Esther Duflo and Abhijit Banerjee, MIT economists whose work has helped transform antipoverty research and relief efforts, have been named co-winners of the 2019 Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel, along with another co-winner, Harvard University economist Michael Kremer. ) (Craig F. Walker/Globe Staff) section: Metro reporter: Coach Patty Barrett

MIT and Harvard professors win Nobel Prize for tackling poverty with careful experiments

At 46, Esther Duflo of MIT is the youngest person ever and only the second woman to win the economics prize in the 50 years it has been awarded.

Investigative reporter Ronan Farrow, author

NBC News hits back against Ronan Farrow’s ‘Catch and Kill’ book

NBC News pushed back against investigative journalist Ronan Farrow on Monday, denying his allegations that the network tried to conceal complaints about former “Today” host Matt Lauer and obstruct Farrow’s reporting into film mogul Harvey Weinstein.

The Gaming Commission awarded a casino license to Wynn five years ago.

CHESTO MEANS BUSINESS

Mohegan’s challenge to Wynn casino license is revived in Suffolk court

Wynn Resorts’ old rival for the Boston-area casino license, Connecticut casino operator Mohegan Sun, hasn’t given up the fight, not by a long shot.

Hong Kong police cleared barricades set up by protesters on Sunday.

As unrest continues, Hong Kong’s economic pain deepens

An unmistakable sense of alarm is spreading among both small-business owners and corporate executives who see no way out of the impasse.

Innovation Economy by Scott Kirsner

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Kirsner’s Innovation Economy column appears in the Boston Sunday Globe, and he contributes to the Globe’s Beta Boston website.